Extended Data Fig. 1: Dose-response study for BrdU/EdU incorporation in mouse hearts.
From: Genetic tracing and topography of spontaneous and stimulated cardiac regeneration in mice
a, Quantification of BrdU/EdU-positive nuclei in the heart of mice injected at P1 with indicated doses of the analog and analyzed after 48 hr (n = 3 different animals; 600 to 2000 total CMs per animal; two-way ANOVA with Šidák’s multiple comparisons). Doses are adjusted to mol/kg. Data are displayed as mean±s.e.m. b, Representative immunofluorescence images (out of at least 40 different images analyzed) for the indicated doses. Scale bar: 20 μm. c, Representative immunofluorescence images (out of at least 40 different images analyzed) used to quantify BrdU- and EdU-positive nuclei. Arrowhead: BrdU/EdU-positive CM. Scale bar: 20 μm.
