Extended Data Fig. 4: Associations of PRS with the risk of TAAD in the UK Biobank examined using the Fine-Gray proportional sub-distribution hazards model.

Cumulative incidence curves were plotted using the cumulative incidence function as implemented in the ‘cmprsk’ R package. Abbreviations: PRS, polygenic risk score; TAAD, thoracic aortic aneurysm and dissection.