Fig. 4: Morphological evaluation of VerMES50 iPSC-PLTs.
From: Defective flow space limits the scaling up of turbulence bioreactors for platelet generation
a TEM images of iPSC-PLTs from VerMES50 set at three speeds. Scale bars: 5 μm (upper panels) and 2 μm (lower panels). b Percentage of iPSC-PLTs positive for vacuoles. VerMES50 at 200: Green bar (N = 10), 300: Purple bar (N = 10), or 400 mm s-1: Orange bar (N = 10). **P < 0.01, Mann-Whitney test vs. 300 mm s-1. c Percentage of iPSC-PLTs positive for abnormal lysosomes. Evaluation methods are described in Methods. **P < 0.01, Mann-Whitney test vs. 300 mm s-1.
