Fig. 4: Lack of direct neuronal responses to 40 kHz ultrasound in brain slices.
From: Low frequency ultrasound elicits broad cortical responses inhibited by ketamine in mice
a Depiction of the In vitro experimental platform where ultrasound was delivered from the bottom of the slice perfusion chamber. b Heatmaps of Ca2+ responses to ultrasound exposure. For the 500 kHz condition, with only 1-s exposure, a single indication line is shown. c Quantitative comparison of the area under the curve (AUC) of Ca2+ responses for 20-s duration after the onset of ultrasound (data expressed as mean ± SEM, statistics: Kruskal–Wallis and Dunn’s multiple comparison tests, ****P < 0.0001).
