Fig. 3: Improvement in symptoms across trajectory classes. | npj Mental Health Research

Fig. 3: Improvement in symptoms across trajectory classes.

From: Trajectories of improvement with repetitive transcranial magnetic stimulation for treatment-resistant major depression in the BRIGhTMIND trial

Fig. 3

Reduction from baseline in HDRS-17 (A), BDI-II (C), and GAD-7 (D) shown for each class at the 8-, 16- and 26-week follow-up time points (time points are measured relative to treatment commencement). Error bars are 95% confidence intervals. Percentage of HDRS-17 responders shown in (B) (values above bars are numbers of responders and total number in each class). Response defined as at least 50% reduction of total score from baseline. HDRS-17 Hamilton Depression Rating Scale, BDI-II Beck Depression Inventory, GAD-7 Generalised Anxiety Disorder Scale. Number of patients in each trajectory class are: Strong improvers (n = 27, 12% of sample), delayed improvers (n = 54, 24%), plateau improvers (n = 47, 21%), non-improvers (n = 88, 39%) and worsening (n = 12, 5%).

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