Table 1 Diversity of spider venom enzymes present in the VenomZone database, showing assigned enzyme classes, families, EC numbers, taxonomic origins and number of proteins for each family

From: Enlightening the toxinological dark matter of spider venom enzymes

Enzyme class

Enzyme family

EC number

Spider family

No. of proteins

Hydrolase

Acetylcholinesterase

3.1.1.7

Barychelidae

1

Phospholipase D

3.1.4.4

Sicariidae

218

Hyaluronidase

3.2.1.-

Ctenidae

Sicariidae

1

1

Isomerase

Reprolysin (M12B family)

3.4.24.-

Lycosidae

1

Astacin (M12A family)

3.4.24.21

Sicariidae

5

Peptidylprolyl isomerase

5.2.1.8

Agelenidae

Ctenidae

2

1

Glycoproteins

CAP

 

Barychelidae

Ctenidae

Lycosidae

1

1

1

Lectin

 

Ctenidae

1

  1. A holistic overview of all components including corresponding references is provided in Supplementary Table 1.