Table 1 Sociodemographic differences in the discovery, validation, Cam-CAN and patient groups
From: The BMIgap tool to quantify transdiagnostic brain signatures of current and future weight
HC | F/Chi-squared | P | Clinical group | F/Chi-squared | P | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Discovery | Validation | Cam-CAN | Schizophrenia | CHR | ROD | |||||
Sample (n) | 770 | 734 | 536 | 46.69a | 7.253 × 10−11 | 146 | 213 | 200 | 776.60a | 2.2 × 10−16 |
BMI, mean (s.d.) | 25.10 (4.03) | 23.03 (2.07) | 25.43 (3.64) | 104.8b | 4.7637 × 10−44 | 24.02 (3.40) | 23.46 (3.42) | 24.01 (3.57) | 13.48b | 1.1456 × 10−8 |
Age, mean (s.d.) | 41.26 (15.51) | 32.24 (12.75) | 54.26 (18.56) | 313.44b | 2.0873 × 10−119 | 30.83 (9.97) | 23.92 (5.24) | 26.02 (6.37) | 164.42b | 3.2518 × 10−86 |
Sex, female, n (%) | 435 (56.49) | 373 (50.82) | 261 (48.69) | 43.65a | 3.32 × 10−10 | 34.00 (23.29) | 103 (48.36) | 96 (48.00) | 590.72a | 2.2 × 10−16 |
Symptoms, mean (s.d.) | ||||||||||
PANSS (total) | NA | NA | NA | NA | NA | 52.26 (29.45) | 52.07 (18.22) | 48.44 (14.26) | 2.08b | 0.13 |
PANSS (positive) | NA | NA | NA | NA | NA | 11.92 (8.13) | 11.31 (4.16) | 8.20 (2.21) | 29.09b | 9.6792 × 10−13 |
PANSS (negative) | NA | NA | NA | NA | NA | 14.98 (9.73) | 13.09 (6.86) | 12.50 (5.66) | 5b | 0.007 |
PANSS (general) | NA | NA | NA | NA | NA | 25.36 (16.13) | 27.66 (10.05) | 27.74 (8.84) | 2.19b | 0.113 |
SANS (total) | NA | NA | NA | NA | NA | 44.44 (26.52) | 27.08 (24.88) | 23.91 (20.95) | 30.69b | 2.4128 × 10−13 |
BDI | 3.55 (5.05) | 3.27 (5.20) | NA | 0.50c | 0.616 | NA | 24.09 (11.75) | 24.56 (12.48) | 182.47b | 3.5659 × 10−60 |
Functioning, mean (s.d.) | ||||||||||
GAF:S past month | 86.30 (6.43) | 87.32 (6.16) | NA | 1.54c | 0.124 | NA | 51.31 (11.29) | 53.92 (13.17) | 503.97b | 3.0021 × 10−125 |
GAF:D past month | 85.49 (6.32) | 86.51 (5.89) | NA | 1.59c | 0.113 | NA | 51.94 (12.) | 54.14 (3.60) | 385.24b | 1.8717 × 10−105 |
GF:S current | 8.50 (0.89) | 8.54 (0.71) | NA | 0.51c | 0.612 | NA | 6.25 (1.75) | 6.39 (1.23) | 157.82b | 6.7860 × 10−55 |
GF:R current | 8.49 (0.77) | 8.59 (0.67) | NA | 1.40c | 0.164 | NA | 5.80 (1.70) | 5.97 (1.81) | 150.54b | 7.1906 × 10−53 |
WHO QoL (total) | 97.45 (33.60) | 102.81 (28.91) | NA | 1.65c | 0.099 | NA | 71.20 (28.81) | 74.92 (24.86) | 39.58b | 8.5257 × 10−17 |
Medications | ||||||||||
Antipsychotics, n (%) | NA | NA | NA | NA | NA | NA | 60 (28.17) | 27 (13.50) | 12.51a | 4.032 × 10−4 |
Antidepressants, n (%) | NA | NA | NA | NA | NA | NA | 105 (49.30) | 137 (68.50) | 4.23a | 0.040 |
CPZ-equivalent (mg) | NA | NA | NA | NA | NA | 358.9 (382.4) | NA | NA | NA | NA |
