Fig. 2: Effect of BDQ and CAP combination on bacterial killing of different M.tb lineages using an escalating checkerboard assay.

The cultures from M.tb strains representing Lineages 1 (M.tb T46, M.tb N0072), 2 (M.tb HN878), and 4 (M.tb Erdman and M.tb N1216) were treated with escalating concentrations of BDQ and CAP in 96-well plates for 7 days. Cultures were stamped onto 7H10 agar plates supplemented with OADC agar for determination of bacterial killing.