Table 3 MIC data for KMR-14-14 against wild-type K. pneumoniae NCTC 13368 and KMR-14-14 resistant isolates in the presence of membrane-interactive agents

From: Convergent evolution of antibiotic resistance mechanisms between pyrrolobenzodiazepines and albicidin in multidrug resistant Klebsiella pneumoniae

View full size image

  1. CCCP carbonyl cyanide m-chlorophenyl hydrazone, an uncoupler of the proton motive force. PAβN phenylalanine-arginine β-naphthylamide, an efflux pump inhibitor. NMP 1-(1-naphthylmethyl)-piperazine, another efflux pump inhibitor. PMBN polymyxin B nonapeptide (PMBN), an outer membrane permeabiliser. Shading indicates a significant result, defined as >2-fold change in MIC.
Back to article page