Fig. 1: Depiction of the neuropharmacology of psychedelic effects on the brain.
From: An Integrated theory of false insights and beliefs under psychedelics
Cortical regions that comprise the DMN (medial prefrontal cortex, posterior cingulate cortex, angular gyrus, and precuneus) are shaded in purple. These DMN regions include the densest expression of 5-HT2A receptors, which psychedelic drugs bind to, resulting in disrupted functioning of the DMN. We note this is a simplified portrait (see de Vos et al.105 for a detailed overview) (created with BioRender.com).
