Table 3 Univariate and multivariate Cox regression analyses for the Child Pugh class A patients only (N = 195): Non-Viral (N = 47), Viral (N = 148).

Age

≥ median vs. < median

0.79;

0.54–1.1

0.21

0.91;

0.66–1.2

0.55

Gender

Male vs. Female

0.83;

0.49–1.4

0.50

1.0;

0.67–1.6

0.93

Cirrhosis

Yes vs. No

0.95;

0.57–1.6

0.84

0.81;

0.53–1.2

0.34

Tumor Size

≥ median vs. < median

1.2;

0.79–1.7

0.45

1.0;

0.72–1.4

0.99

Extrahepatic

Yes vs. No

1.0;

0.69–1.5

0.96

1.0;

0.73–1.4

0.94

PVTT

Yes vs. No

1.3;

0.86–1.8

0.25

0.93;

0.67–1.3

0.65

PVTT Class

vp 3–4 vs. vp 0–2

1.1;

0.75–1.7

0.56

0.98;

0.70–1.4

0.91

MVI

Yes vs. No

1.3;

0.91–1.9

0.15

1.0;

0.73–1.4

0.98

ECOG PS

 ≥ 1 vs. 0

1.2;

0.75–1.9

0.35

1.5;

1.0–2.2

0.034**

1.5;

1.0–2.2

0.038**

BMI

 ≥ 25 vs. < 25

0.96;

0.65–1.4

0.85

1.1;

0.82–1.6

0.45

BCLC Stage

C vs. A/B

1.2;

0.78–1.9

0.41

0.94;

0.66-1.4

0.75

AFP

 < 400 vs. ≥ 400

1.2;

0.8–1.7

0.41

0.96;

0.69–1.3

0.79

Etiology

Non-Viral vs. Viral

1.8;

1.2–2.7

0.005**

2.0;

1.4–2.8

<0.001**

1.9;

1.3–2.7

<0.001**

ICI Regimen

Combo vs. Mono

0.7;

0.47–1.2

0.18

0.65;

0.46–0.94

0.020**

0.73;

0.51–1.1

0.096

Concurrent LRT

Yes vs. No

1.3;

0.86–1.8

0.24

1.1;

0.81–1.5

0.49