Table 2 Coefficient of change in eGFR per year in the two years following initiation of systemic therapy (average change in eGFR per year and for specific patient groups per year).

From: The impact of VEGF signalling pathway inhibitors and/or immune checkpoint inhibitors on kidney function over time: a single centre retrospective analysis

Patient group

Coefficient of eGFR change per year (mL/min/1.73m2)

95% CI: lower

95% CI: upper

p-value

Whole cohort (unadjusted)

+1.03

−1.64

+3.70

0.23

Nephrectomy prior to systemic therapy

+2.30

−1.66

+6.26

0.52

Metastatic cancer at the point of diagnosis

−0.18

−5.25

+4.89

0.648

Average eGFR < 60 prior to systemic therapy

−1.02

−6.55

+4.50

0.473