Fig. 5: Ten-year absolute risk of breast cancer by the PRS percentiles. | BJC Reports

Fig. 5: Ten-year absolute risk of breast cancer by the PRS percentiles.

From: Breast cancer risk assessment based on susceptibility genes and polygenic risk score in Vietnamese women

Fig. 5

The ten-year absolute risk of developing BC was estimated for different PRS percentiles: >99% (a), 95–99% (b), 90–95% (c) and 80–90% (d). Data were re-sampled for 100 times and each gray dot corresponds to the approximated risk of one re-sampled dataset. The blue dots show the mean, the area bounded by green lines is 95% confidence intervals, the red curve is generated by a generalized additive model with smoothing spline. The red vertical lines correspond to the age at which the smooth red curve reaches 2.3% risk threshold.

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