Table 2 Reported binding affinities of OXTR in different species and cell lines
From: Predicting oxytocin binding dynamics in receptor genetic variants through computational modeling
Cells | Kd value (nM) Mean ± SD | Method | Reference |
|---|---|---|---|
Myometrial (Nonpregnant Human) | 0.96 ± 0.48 | Radioligand Binding | Fuchs et al.65 |
Myometrial (Nonpregnant Human) | 3.33 ± 0.50 | Den et al.46 | |
Myometrial (1st trimester Human) | 2.71 ± 1.03 | ||
Myometrial (Term Human) | 1.87 ± 0.3 | ||
Myometrial (Term Human) | 1.2 ± 0.21 | Rezapour et al.66 | |
Myometrial (Term Human) | 1.6$ | Phaneuf et al.25 | |
Myometrial (Term Human) | 1.7 ± 0.46 | Fuchs et al.67 | |
Myometrial (Term Human) | 0.93 ± 0.29 | Rivera et al.68 | |
Myometrial (Rat) | 1.21 ± 0.34 | Anouar et al.23 | |
Myometrial (Guinea pig) | 2.6 ± 0.1 | Kojro et al.69 | |
Transfected HEK293 | 0.56$ | Gulliver 202026 | |
Transfected HEK293 | 1.4 ± 0.2 | Waltenspühl et al.27 | |
Myometrial (Guinea Pig) | 1.5 ± 0.1 | Photoaffinity labeling | Klein et al.70 |
Myometrial (Guinea Pig) | 2.6 ± 0.2 | Fahrenholz et al.71 | |
Myometrial (Cattle) | 2.52 | Binding Isotherm | Pliska et al.24 |
Myometrial (Sheep) | 4.04 | ||
Myometrial (Rat) | 9.32 |
