Fig. 1: Characterization of AS03-like emulsions, with and without TLR agonists.

A The concentrations of squalene, INI-2002, and INI-4001 in each starting emulsion created for these studies, and the mean particle size and polydispersity index for each. B Cryo-TEM images of each emulsion shown in (A), plus the resulting emulsion after mixing of the INI-4001 and INI-2002 emulsions. C Example UHPLC chromatograph showing the distinct peaks for INI-2002, INI-4001, DL-α-tocopherol, and squalene.