Fig. 2: Simulating the evolutionary dynamics of digital quasispecies in silico.
From: Quasispecies theory and emerging viruses: challenges and applications
a Single-peak fitness landscape (illustrated with a 3-bits hypercube). The size of the balls is proportional to the genotypes’ fitness. The quasispecies population plots show the error threshold for the single-peak fitness landscape for geometric (b) and stamping machine (c) replication. d Fitness landscape with antagonistic epistasis also for 3-bit genomes where the effects of mutations are less severe in combination than individually. Here, we also display the error threshold for geometric (e) and stamping machine (f) replication modes. All the diagrams show the stationary populations of the master sequence (000, thick lines) and the pool of mutants (with 1, 2, or 3 mutations, thin lines) averaged over 200 replicas at increasing the per-bit mutation probability. The dashed orange lines indicate the critical per-bit mutation rate causing the error threshold. See Ref. 50 for further details.
