Fig. 3: Pathological analysis of seal hepatovirus infected liver tissues.
From: Hepatovirus infections in juvenile seals from the North Sea
A H&E staining. Liver section of seal PV20121801. No inflammation in the liver tissue and presence of morphologically normal hepatocytes. Bar: 50 µm. B FISH. Liver section of seal PV20121801. Seal hepatovirus RNA is detected within the cytoplasm of normal hepatocytes (arrowheads). C H&E staining. Liver section of seal PV20010801. Focal liver necrosis (asterisk) with accumulation of debris and granulocytic and histiocytic infiltration. Bar: 50 µm. D FISH. Liver section of seal PV20010801. No FISH signal within the necrotic areas, positive staining within individual adjacent hepatocytes (arrows). Bar: 20 µm.
