Fig. 5: α7/L-AChBP chimera (PDB ID: 4HQP) docked with HSV1 gD (PDB ID: 2C36). (Docking pose 4).
From: HSV1 glycoprotein D utilizes an LY6-like binding domain to inhibit alpha7 nicotinic receptors
a Docking of HSV-1 gD (red) with α7/L-AChBP chimera (blue). Pose 4 indicates an interaction at the interface between subunits, near the orthosteric binding site. b Detail, showing α7/L-AChBP subunits chain A (blue) and chain B (orange) docked with HSV1 gD (red). The region labeled α1’ indicates the α-BgTx homologous binding loop of HSV1 gD (G83–P92).
