Fig. 6: VMD contact map between α7/L-AChBP chains and HSV1 gD (pose 4).
From: HSV1 glycoprotein D utilizes an LY6-like binding domain to inhibit alpha7 nicotinic receptors
Ligand and receptor amino acids within the binding region are placed on the X-axis and Y-axis. All amino acid residues that are in close contact will appear on the map with dark shading. More distant contacts are visualized as lighter shades. a VMD contact map between α7/L-AChBP chain A and HSV1 gD ectodomain (pose 4). The contact map indicates close contact between residues in α7 chimera chain A (Y184, E185, and C186) and the HSV1 gD loop region (R89, K90, Q91). b α7/L-AChBP chimera chain B alignment with HSV1 gD ectodomain. The contact map shows interacting residues between α7 chimera chain B amino acids (M156, Q157, and E158) are in close contact with the HSV1 gD amino acids I80, V81, G83, A84, S85, V88, R89.
