Fig. 3: Mouse skin-inflammation model induced by plasma irradiation.
From: In vivo redox imaging of plasma-induced skin-inflammation in mice
A Three different sites were chosen on the shaved mouse back: the upper site was irradiated with direct mode plasma for 5 min, the middle was irradiated with remote mode plasma for 10 min, and the lower was irradiated with helium gas only for 10 min. The animal’s back was photographed immediately after irradiation (0 h) and at various time intervals to demonstrate the lesion’s progression. B Progression of the skin injury area after plasma irradiation until complete healing, occurring 16 days after irradiation (n = 4 per group). The (*) indicates statistically significant differences between the two groups at the p < 0.05 level, as determined by a one-tailed t-test assuming equal variance. C Thermography measurement: skin-surface temperature was measured after 10-min of plasma irradiation in remote mode. The skin-surface temperature was 42.5 °C. D Histopathology of skin samples irradiated by either remote or direct plasma irradiation, collected at 2 and 24 h after irradiation, fixed, and examined by regular histopathological procedures.
