Table 3 Summary of potential findings based on model performance across different input formats.

From: Focal cortical dysplasia (type II) detection with multi-modal MRI and a deep-learning framework

Aspects

Classification tasks

MRI

DL models

Remarks

Modes (Iacs)

Planes

FCD-II

FCD-II vs. HCs

T1w

ax(T1w)

Xception/ DenseNet201

• Xception and DenseNet201 show the best performance.

Subtypes

FCD-IIa vs. FCD-IIb

FLAIR/T1w

Sg (FLAIR/T1w)

DenseNet201

• DenseNet201 displays remarkable performance.

Age

Adolescents vs. HCs

FLAIR/T1w

ax(FLAIR)/ cr(T1w)

DenseNet201

• The DenseNet201 depicts remarkable outcomes.

• The axial plane of both MRI modes performs better in FCD-II lesion detection.

Adults vs. HCs

T1w

ax(T1w)

IIa vs. IIb (in adults)

FLAIR/T1w

-

Sex

Female patients vs. HCs

T1w

cr (FLAIR/T1w)

Xception/ DenseNet201

• Coronal and sagittal planes showed more distinct and diverse features.

• DenseNet201 recorded the highest performance scores.

Males vs. HCs

T1w

sg (T1w)

DenseNet201

Females vs. Males

T1w

cr/ sg (T1w)

IIa vs. IIb (in females)

FLAIR/T1w

-

IIa vs. IIb (in males)

T1w

-

Brain hemisphere

FCD-II in left vs. right

FLAIR/T1w

sg (FLAIR)/ ax (T1w)

DenseNet201

• FCD-II lesions in axial and sagittal planes were well distinguished.

• The DenseNet201 showed promising results.

IIb in left vs. right

FLAIR/T1w

ax (T1w)

Brain lobes

frontal vs. parietal

T1w

ax (T1w)

DenseNet201

• Well detected in T1w MRI mode and the axial imaging plane.

• DenseNet201 produced noteworthy outcomes.

IIa vs. IIb (in frontal)

T1w

sg (FLAIR)/ax (T1w)