Table 1 Proteinopathy imaging targets and associated radiotracers discussed herein
From: Emerging targets for positron emission tomography imaging in proteinopathies
Target | Radiotracers |
|---|---|
Mutant huntingtin protein (mHTT) | [11C]CHDI-180L |
[11C]CHDI-180R | |
[11C]CHDI-626 | |
[18F]CHDI-650 | |
β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) | [18F]PF-06684511 |
[11C]RO6807936 | |
O-linked β-N-acetylglucosamine hydrolase (OGA) | [18F]MK8553 |
[11C]LSN3316612 | |
[18F]LSN3316612 | |
[11C]BIO-735 | |
[11C]BIO-578 | |
Cholesterol 24-hydroxylase (CH24H) | [11C]1 |
[18F]T-008 | |
[18F]Cholestify | |
Transactive response DNA binding protein of 43 kDa (TDP-43) | AC Immune Compounds |