Table 1 Proteinopathy imaging targets and associated radiotracers discussed herein

From: Emerging targets for positron emission tomography imaging in proteinopathies

Target

Radiotracers

Mutant huntingtin protein (mHTT)

[11C]CHDI-180L

[11C]CHDI-180R

[11C]CHDI-626

[18F]CHDI-650

β-Site amyloid precursor protein cleaving enzyme 1 (BACE1)

[18F]PF-06684511

[11C]RO6807936

O-linked β-N-acetylglucosamine hydrolase (OGA)

[18F]MK8553

[11C]LSN3316612

[18F]LSN3316612

[11C]BIO-735

[11C]BIO-578

Cholesterol 24-hydroxylase (CH24H)

[11C]1

[18F]T-008

[18F]Cholestify

Transactive response DNA binding protein of 43 kDa (TDP-43)

AC Immune Compounds