Fig. 2: New developments in copper-mediated radiolabeling.
From: Copper-mediated radiochemistry: historical impact, current trends, and future possibilities
A Improved copper-mediators and solvents for CMRF35. B The directed (DG: Directing Group) radiofluorination of aryl halides with a Cu-N-Heterocycle-carbene (Cu-NHC)45. C Improved CMRF conditions for the suppression of protodeborylated byproduct formation39. D Aminoquinoline-directed CMRF of aromatic C-H bonds43. E The CMRF of aryl C-H bonds via the in-situ formation of aryl iodonium salts42. F Selective Sequential Ir/Cu-mediated radiofluorination of Ar C-H bonds41.
