Table 1 Diurnal APAs from genes with ≥2 APA sites (20 lowest median meta2d p-values)

From: Sleep and diurnal alternative polyadenylation sites associated with human APA-linked brain disorders

PAS_ID

Symbol

Chromosome

Strand

Peak

PASs/gene

Total

median p

median BH.Q

AVE phase

AVE Amp

AVE rAmp

497,844

Parvb

7

+

115,445,766

2

6707

1.30E-10

1.91E-06

1.89

373

0.29

251,968

Dnajb1

19

-

24,522,731

2

4379

1.09E-09

6.93E-06

15.54

194

0.24

424,776

Ccdc107

5

+

57,752,233

3

1833

1.13E-08

4.15E-05

18.14

124

0.37

282,515

Rap1gds1

2

-

227,512,038

2

45

8.29E-09

3.62E-05

18.35

10

1.29

86,566

Hint1

10

+

38,993,254

3

44,628

1.01E-08

3.73E-05

11.56

1871

0.22

42,414

Dbp

1

+

96,180,614

2

5424

2.19E-08

5.35E-05

11.88

408

0.40

496,957

Cacna1i

7

+

111,947,418

3

2361

3.52E-08

7.46E-05

0.81

112

0.24

301,149

S100a10

2

+

179,229,660

2

863

4.75E-08

9.48E-05

21.50

88

0.59

249,570

Ndrg4

19

-

9,351,408

2

57,912

5.93E-08

1.11E-04

0.75

2119

0.19

141,758

Iars2

13

-

96,831,484

3

263

5.83E-08

9.74E-05

18.22

33

0.73

89,040

Phf23

10

+

54,722,784

2

2014

7.00E-08

1.15E-04

13.48

119

0.32

455,360

Wdr35

6

+

31,831,183

5

154

6.21E-08

9.86E-05

18.05

23

0.83

279,711

Prpf38b

2

-

196,553,983

3

397

1.05E-07

1.47E-04

19.09

34

0.48

363,773

Cacna2d1

4

-

18,950,614

2

3218

1.05E-07

1.51E-04

5.00

248

0.39

309,907

Cbs

20

-

9,708,260

4

3085

1.65E-07

2.18E-04

21.42

165

0.30

214,595

Faf2

17

-

9,947,225

4

2246

2.24E-07

2.29E-04

15.60

105

0.26

447,907

Syndig1l

6

-

104,323,418

2

253

2.17E-07

2.46E-04

8.92

36

0.77

470,887

Btbd11

7

-

18,035,151

3

3401

3.07E-07

3.36E-04

23.59

184

0.29

449,908

Dicer1

6

-

123,627,529

3

296

3.65E-07

4.14E-04

17.00

30

0.58

549,543

Coq10b

9

+

56,573,671

2

334

2.07E-07

2.43E-04

16.60

32

0.54

  1. PAS_ID is a unique identifier for each PAS. Gene Symbol, Chromosome are listed, as well as Strand according to the convention of each chromosome. Peak is the mode or most common 3′ endpoint in the cluster. The number of PASs per gene is listed. Total refers to the sum of the reads for all samples.
  2. Meta2d calculations shown are: median p median probability of cycling, median BH.Q median Benjamini/Hochberg adjusted probability, AVE phase average peak phase, AVE Amp average amplitude (from peak to trough) of reads, and AVE rAmp average relative amplitude adjusted by the mean read number.