Fig. 2: Analysis of proteins with statistically significant 24-hour rhythms. | npj Biological Timing and Sleep

Fig. 2: Analysis of proteins with statistically significant 24-hour rhythms.

From: Challenges and opportunities for statistical power and biomarker identification arising from rhythmic variation in proteomics

Fig. 2

A Node and edge relationships of proteins identified as having statistically significant 24-hour rhythms (p value < 0.05) and forming a functionally enriched cluster. Network nodes represent proteins and edges represent protein-protein interactions, line thickness indicates the strength of data support (B) polar plot of acrophases of proteins shown in Fig. 3A, amplitude is shown in terms of z-score along the radius, DLMO time is shown around the perimeter (DLMO 0 = clock time 22:46 h:min). All analyses based on a cohort of n = 10.

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