Fig. 1: Graphical representation of the range of strain loading conditions associated with physiological and pathological processes of the body.

a Simplified graphical representation and b scatter plot of strain rate versus strain magnitude plot of various physiological and pathological processes. Processes are grouped by the relevant organs and tissues. Values for strain obtained for different tissues including bones191,192,193,194,195, lungs56,196,197, ligaments198,199, and cartilage200; brain61,62,63,64,65,66,71,72,201, heart52,57,58,196, skin55 and intestines202. Each point plotted represents the average value from an individual study. The bounding lines are qualitative and are for visual reference only.