Fig. 3: Comparison of tissue-specific normal and cancer cell behavior in terms of cell area and stiffness.
From: Tissue-dependent mechanosensing by cells derived from human tumors
a, d Breast, b, e lung, and c, f prostate cell lines on soft (500 Pa) and stiff (30 kPa) PAAm Coll and FN substrates, soft (500 Pa) HA substrates coated with Coll and FN, and glass. (N) refers to non-malignant (normal) cell lines. See also Supplementary Figs. 8 and 9. ***p < 0.01; **p < 0.05; *p < 0.1, adjusted for multiple testing using Benjamini-Hochberg procedure. The number of measurements for the physical feature of interest is at least 25 (n ≥ 25) for each cell line on a particular substrate. See Supplementary Tables 1 and 2 for the exact value of n for the cell lines.
