Fig. 1: Intra- and inter-mouse variability of magnitude, diffusion, and tumor originating pathline density. | npj Biomedical Innovations

Fig. 1: Intra- and inter-mouse variability of magnitude, diffusion, and tumor originating pathline density.

From: Interstitial fluid transport dynamics predict glioblastoma invasion and progression

Fig. 1

A Heat map of tumor and surrounding contrast-enhancing parenchyma IFF magnitude (um/s) with the tumor (blue boundary) and contrast-enhancing parenchyma (yellow boundary) (Scale bar = 500 µm). B Distribution of magnitudes within GL261 Mouse 1. C IFF magnitude of all pixels within the surrounding contrast-enhancing parenchyma for each GL261 mouse. Compact letter display shows columns are statistically indistinguishable if and only if they share at least one letter. D IFF magnitude of all pixels within the surrounding contrast-enhancing parenchyma for each GSC mouse. E Heat map of tumor and surrounding contrast-enhancing parenchyma IFF diffusion coefficient (um2/s) (Scale bar = 500 µm). F Distribution of diffusion coefficients within GL261 Mouse 1. G IFF diffusion coefficient of all pixels within the surrounding contrast-enhancing parenchyma for each GL261 mouse. H IFF diffusion coefficient of all pixels within the surrounding contrast-enhancing parenchyma for each GSC mouse. I Tumor-originating pathlines (dark red is initial location moving to ending location as bright yellow) (Scale bar = 500 µm). J Density heatmap of tumor-originating pathlines where blue and red represent a low and high tumor-originating pathline density, respectively (Scale bar = 500 µm). K Tumor originating pathline density of all pixels within the surrounding contrast-enhancing parenchyma for each GL261 mouse or location. L Tumor originating pathline density of all pixels within the surrounding contrast-enhancing parenchyma for each GSC mouse or location.

Back to article page