Fig. 8: Comparative metabolomic analysis of significant metabolites in VaD compared to AD groups.
From: Metabolomic profiling of a dementia cohort in Egypt: a step towards a neuro-exposome model
A Volcano plot displaying the distribution of significant metabolites in VaD compared to AD patients based on Log2 (fold change) and -Log10 (FDR-adjusted p-value). Metabolites with FDR P < 0.01 are highlighted in red, those with FDR P < 0.05 in green, FDR P < 0.1 (exploratory) in blue, and non-significant metabolites (FDR P > 0.1) in gray. B Box plots representing the relative abundance of significant metabolites in AD versus VaD patients, illustrating variations in metabolite intensity across groups. Metabolites with FDR P < 0.01 are labeled (***), those with FDR P-values < 0.05 are labeled (**), and FDR P < 0.1 are labeled (*). The volcano plots provide an overview of metabolite significance and fold change, while the box plots emphasize individual metabolite differences between AD and VaD patients.
