Table 4 Comparison of Model 1 and Model 2 results with the inclusion of BMI

From: Smoking predicts brain atrophy in 10,134 healthy individuals and is potentially influenced by body mass index

Brain region

p valuea Model 1

p valuea Model 2

R2 Model 1

R2 Model 2

ΔR2

Gray Matter

3.645e-12

1.633e-07

7.045e-03

4.006e-03

−3.039e-03

White Matter

5.441e-13

1.639e-08

7.587e-03

4.655e-03

−2.932e-03

Lateral Ventricle

8.844e-02

2.238e-01

4.247e-04

2.166e-04

−2.081e-04

Frontal Lobe

1.275e-13

7.959e-09

8.002e-03

4.860e-03

−3.142e-03

Temporal Lobe

7.201e-13

4.226e-08

7.508e-03

4.387e-03

−3.121e-03

Parietal Lobe

4.498e-09

2.033e-05

5.021e-03

2.654e-03

−2.367e-03

Occipital Lobe

5.782e-06

3.863e-03

3.004e-03

1.221e-03

−1.783e-03

Hippocampus

1.476e-10

1.201e-06

5.991e-03

3.445e-03

−2.546e-03

Cerebellum

2.695e-08

7.869e-05

4.515e-03

2.279e-03

−2.236e-03

Posterior Cingulate

1.883e-13

5.380e-09

7.890e-03

4.971e-03

−2.919e-03

Precuneus

8.845e-05

1.262e-02

2.247e-03

9.101e-04

−1.337e-03

  1. aCorrected for multiple comparisons.