Abstract
This paper presents the results of a study on the pathological changes associated with post traumatic central spinal cord necrosis.
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Albin, M S, White, R J, Acosta-Rua, G & Yashon, D (1968). Study of functional recovery produced by delayed localized cooling after spinal cord injury in primates. J. Neurosurg. 29, 113–120.
Allen, A R (1911). Surgery of experimental lesion of spinal cord equivalent to crush injury of fracture dislocation of spinal column: a preliminary report. J. American Med. Assoc. 57, 878–880.
Barnes, R (1948). Paraplegia in cervical spinal injuries. J. Bone & Joint Surg. 30B, 234–244.
Bedbrook, G M (1966). Pathological principles in the management of spinal cord trauma. Paraplegia, 4, 43–56.
Black, P & Markowitz, R S (1971). Experimental spinal cord injury in monkeys: comparison of steroids and local hypothermia. Surg. Forum, 22, 409–411.
Chomiak, M, Lewandowski, M, Lutnicki, W & Milart, Z (1960). Versuche zur Bestimmung der Rückenmarkbahnen beim Schaf mittels der Degenerationsmethode. Ann. Univ. M. Curie-Sklofowska, D.D. 15, 65.
Dohrmann, C J, Wagner, F C Jr. & Bucy, P C (1972). Transitory traumatic paraplegia: electron microscopy of early alterations in myelinated nerve fibers. J. Neurosurg. 36, 407–415.
Dohrmann, G J, Wick, K M & Bucy, P C (1973). Spinal cord blood flow patterns in experimental traumatic paraplegia. J. Neurosurg. 38, 52–58.
Ducker, T B & Hamit, H F (1969). Experimental treatments of acute spinal cord injury. J. Neurosurg. 30, 639–697.
Freeman, L W (1952). Return of function after complete transection of the spinal cord of the rat, cat and dog. Annals of Surgery, 136, 193.
Fried, L C & Goodkin, R (1971). Microangiographic observations in the experimentally traumatized spinal cord. J. Neurosurg. 35, 709–714.
Fulton, J F (1950). A Textbook of Physiology, 16th edition. Saunders, Philadelphia.
Green, B A, Wagner, F C Jr. & Bucy, P C (1971). Edema formation within the spinal cord. Trans. Amer. Neurol. Assoc. 96, 244–245.
Hartzog, J T, Fisher, R G & Snow, C (1969). Spinal cord trauma; effect of hyperbaric oxygen therapy. Proc. Annu. Clin. Spinal Cord Inj. Conf. 17, 70–71.
Hinwood, B, Yeo, J D & Kidman, A D (1974). Catecholamine levels in the sheep's spinal cord following trauma. Proc. of the Australian Biochemistry Society, 7, 29.
Hinwood, B G, Yeo, J D & Kidman, A D (1975). Molecular pathology of spinal injuries. The monoamine hypothesis. Proc. Aust. Biochem. Soc. 8, 60.
Kelly, D L, Lassiter, K R L, Calogero, J A & Alexander, E (1970). Effects of local hypothermia and tissue oxygen studies in experimental paraplegia. J. Neurosurg. 33, 554–563.
Kelly, D L, Lassiter, K R L, Vonsgsvivut, A & Smith, J M (1972). Effects of hyperbaric oxygenation and tissue oxygen studies in experimental paraplegia. J. Neurosurg. 36, 425–429.
Kobrine, A I & Martins, A N (1974). Spinal cord blood flow and neurological dysfunction. Lancet, April 27.
Kobrine, A I (1975). The neuronal theory of experimental traumatic spinal cord dysfunction. Surg. Neurol. 3, 21.
Kobrine, A I, Doyle, T & Rizzoli, H (1967). Further studies on histamine in spinal cord injury and post traumatic hyperemia. Surg. Neurol. 5, 101–103.
Lassek, A M (1942). The pyramidal tract; a fibre and numerical analysis in a series of non-digital mammals (ungulates). J. Comp. Neurol. 77, 399.
Locke, G E, Yashon, D & Feldman, R A et al. (1971). Ischaemia in primate spinal cord injury. J. Neurosurg. 34, 614–617.
Naftchi, N E, Demeny, M, Decrescito, V, Tomasula, J, Flamm, E & Campbell, J (1974). Biogenic amine concentration in traumatised spinal cords of cats. J. Neurosurg. 40, 52–57.
Osterholm, J L, Mathews, G F & Irvin, J D et al. (1971). A review of altered norepinephrine metabolism attending severe spinal injury: results of alpha methyl tyrosine treatment and preliminary histofluorescent studies. Proc. Veterans Admin. Spinal Cord Inj. Conf. 18, 17–21.
Osterholm, J L (1974). The pathophysiological response to spinal cord injury—current status. J. Neurosurg. 40, 5–33.
Osterholm, J L & Mathews, G J (1972). Altered norepinephrine metabolism following experimental spinal cord injury. 1. Relationship to haemorrhagic necrosis and post-wounding neurological deficits. J. Neurosurg. 36, 386–394.
Osterholm, J L & Mathews, G J (1972). Altered norepinephrine metabolism following experimental spinal cord injury. II. Protection against traumatic spinal cord haemorrhagic necrosis by norepinephrine synthesis blockade with alpha methyl tryosine. J. Neurosurg. 36, 395–401.
Palmer, A C (1965). Introduction to Animal Neurology, 1st edition. Blackwell Scientific Publications, Oxford.
Salthouse. (1965). Luxol fast blue for staining phospholipids. J. Histochem. Cytochem. 13, 133.
Schneider, R D (1958). The syndrome of acute central cervical spinal cord injury. J. Neurol. Neurosurg. Psychiat. 21, 216.
Tator, C H (1972). Acute spinal cord injury: a review of recent studies of treatment and pathophysiology. C.M.A. Journal, July 22, 107, 143–150.
Tomasula, J J, Decrescito, V & Goodkin, R et al. (1969). A survey of the management of experimental spinal cord trauma. Proc. Annu. Clin. Spinal Cord Inj. Conf. 71, 12–16.
Turnbull, I M (1971). Microvasculature of the human spinal cord. J. Neurosurg. 35, 141–147.
Vise, W M, Yashon, D & Hunt, W E (1974). Mechanisms of norepinephrine accumulation within sites of spinal cord injury. J. Neurosurg. 40, 76–82.
Wagner, F C Jr., Green, B A & Bucy, P C (1971). Spinal cord edema associated with paraplegia. Proc. Clin. Spinal Cord Injury Conf.
White, R J & Albin, M S (1970). Spine and spinal cord injury. In: Gurdjian, E.S., Lane, W. A., Patrick, L. M., (eds): Impact Injury and Crash Protection. Charles C. Thomas, Publisher, Springfield, Ill., pp. 63–85.
Yeo, J D, Payne, W & Collins, L T (1971). Controlled experimental contusion of the spinal cord of sheep. Proceedings of the Surgical Research Society of Australasian Scientific Meeting. Aust. & N.Z. J. Surgery, 41, no. 1, 89–90.
Yeo, J D & Collins, I (1974). The place of isotope myelography in the definition of spinal cord swelling following trauma. Aust. & N.Z. J. Surgery, 44, no. 3, 292–298.
Yeo, J D & Payne, W H (1975). Sequential pathological changes seen in controlled trauma to the spinal cord of the sheep. Ann. Meeting Royal College of Pathologist. of Aust., Aukland, N.Z. J. Pathology, 7, no. 1 66.
Yeo, J D, Payne, W, Hinwood, B & Kidman, A (1975). The experimental contusion injury of the spinal cord in sheep. Paraplegia, 12, 275.
Yeo, J D, Mckenzie, B, Hinwood, B & Kidman, A (1976). Treatment of paraplegic sheep with hyperbaric oxygen—a preliminary report. Med. J. of Aust. 1, 538–540.
Zivin, J A, Doppman, J L, Reid, J L, Tappaz, M L, Saavedra, J M, Dopin, I J & Jacobowitz, D M (1976). Biochemical and histochemical studies of biogenic amines in spinal cord trauma. Neurology, 26, 99–107.
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Yeo, J., Stabback, S. & McKenzie, B. Central necrosis following contusion to the sheep's spinal cord. Spinal Cord 14, 276–285 (1977). https://doi.org/10.1038/sc.1976.45
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DOI: https://doi.org/10.1038/sc.1976.45