Abstract
Fifty acute SCI patients are reviewed retrospectively for incidence of deep vein thrombosis and pulmonary embolism and the problems encountered in the diagnosis. The possible role of some risk factors in triggering thromboembolism and the consequent implications in anticoagulant therapy are discussed.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Adar, R & Salzman, E W (1975). Treatment of thrombosis of veins of the lower extremities. New Eng. J. Med., 292, 348.
Altemeier, W A, Hill, E O & Fullen, W D (1969). Acute and recurrent thromboembolic disease: a new concept in etiology. Ann. Surg., 170, 547.
Bergofsky, E H (1964). Mechanism for respiratory insufficiency after cervical cord injury. Ann. Intern. Med., 61, 435.
Brogam, O (1977). The role of bacterial L form in urinary tract infections. Br. J. Urol., 49, 43.
Casas, E R, Sanchez, M P, Arias, C R & Masip, J P (1976). Prophylaxis of venous thrombosis and pulmonary embolism in patients with acute traumatic spinal cord lesions. Paraplegia, 14, 178.
Gurewich, V & Hutchinson, E (1971). Detection of intravascular coagulation by a serial dilution protamine sulfate test. Ann. Intern. Med., 75, 895.
Guttmann, L (1973). Spinal Cord Injuries, 1st edn. Blackwell Scientific Publications, Oxford, p. 179.
Hachen, H J (1974). Anticoagulant therapy in patients with spinal cord injury. Paraplegia, 13, 176.
Johnston, K W, Kakkar, V V & Spindler, J J (1974). A simple method for detecting deep vein thrombosis: an improved electrical impedance technique. Am. J. Surg., 127, 349.
Mckay, D G & Shapiro, S A (1958). Alterations in blood coagulation system induced by bacterial endotoxin I in vivo (Generalized Schwartzman reaction). J. Exp. Med., 107, 353.
Naso, F (1974). Pulmonary embolism in acute spinal cord injury. Arch. Phy. Med. Rehabil., 55, 275.
Philipps, R S (1963). Incidence of deep venous thrombosis in paraplegia. Paraplegia, 1, 116.
Robin, E D (1977). Overdiagnosis and overtreatment of pulmonary embolism. Ann. Intern. Med., 87, 775.
Seaman, A J (1970). Recognition of intravascular clotting; plasma protamine paracoagulation test. Arch. Intern. Med., 125, 1016.
Sevitt, S & Gallagher, N G (1961). Prevention of venous thrombosis and pulmonary embolism in injured patients. Lancet, 2, 981.
Shull, J R & Rose, D L (1966). Pulmonary embolism in patients with spinal cord injuries. Arch. Phys. Med. Rehabil., 47, 444.
Silver, J R (1974). The prophylactic use of anticoagulant therapy in the prevention of pulmonary emboli in one hundred consecutive spinal injury patients. Paraplegia, 12, 188.
Silver, J R & Moulton, A (1970). Prophylactic anticoagulant therapy against pulmonary emboli in acute paraplegia. Br. Med. J., 2, 338.
Sullivan, N M, Sutter, V L, Carter, N T, Attebery, H R & Finegold, S M (1972). Bacteremia after genitourinary tract manipulations: Bacteriological aspects and evaluation of various blood culture systems. Appl. Microbiol., 23, 1101.
Szucs, M M, Brooks, H L, Grossman, W, Banas, J S, Meister, S G, Dexter, L & Dalen, J E (1971). Diagnostic sensitivity of laboratory findings in acute pulmonary embolism. Ann. Intern. Med., 74, 161.
Todd, J W, Frisbie, J H, Rossier, A B, Adams, D F, Als, A V, Armenia, R J, Sasahara, A A & Tow, D E (1976). Deep venous thrombosis in acute spinal cord injury: a comparison of 125I fibrinogen leg scanning, impedance plethysmography and venography. Paraplegia, 14, 50.
Tribe, C R (1963). Causes of death in early and late stages of Paraplegia. Paraplegia, 1, 19.
Walsh, J J & Tribe, C R (1965). Phlebo-thrombosis and pulmonary embolism in paraplegia. Paraplegia, 3, 209.
Warlow, C, Ogston, D & Douglas, A S (1972). Venous thrombosis following strokes. Lancet, 1, 1305.
Watson, N (1968). Venous thrombosis and pulmonary embolism in spinal cord injury. Int. J. Paraplegia, 1, 113.
Watson, N (1974). Anticoagulant therapy in the treatment of venous thrombosis and polmonary embolism in acute spinal injury. Paraplegia, 12, 197.
Wright, H P & Osborn, S B (1952). Venous velocity in bed ridden medical patient. Lancet, 2, 699.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Perkash, A., Prakash, V. & Perkash, I. Experience with the management of thromboembolism in patients with spinal cord injury: part I. incidence, diagnosis and role of some risk factors. Spinal Cord 16, 322–331 (1978). https://doi.org/10.1038/sc.1978.62
Issue date:
DOI: https://doi.org/10.1038/sc.1978.62