Abstract
Serum lipid fractions were studied in ten patients with chronic renal failure (CRF) associated with long-standing spinal cord injury (SCI). A group of age-and-sex-matched patients with long-standing SCI but normal renal function were included for comparison. Serum triglycerides were markedly elevated in SCI-CRF patients. Both SCI groups exhibited moderate hypocholesterolemia. High density lipoprotein (HDL) cholesterol was severely reduced in the SCI-CRF group and moderately reduced in the SCI-control group. Chronic renal failure, reduced physical activity and several other factors may be operative in the genesis of hypertriglyceridemia and reduced HDL-cholesterol levels in this condition. Further investigations are necessary to examine the possible effect of these lipid abnormalities on the cardiovascular system in these patients.
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Vaziri, N., Gordon, S. & Nikakhtar, B. Lipid abnormalities in chronic renal failure associated with spinal cord injury. Spinal Cord 20, 183–189 (1982). https://doi.org/10.1038/sc.1982.34
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DOI: https://doi.org/10.1038/sc.1982.34
