Abstract
Two patients with intractable constipation and an atonic bladder due to a partial spinal cord lesion and sacral nerve lesion are described.
Treatment with cisapride (4 × 10 mg daily) was undertaken. After a few days the stool passed spontaneously. The effect was dose-dependent and has been maintained for at least 40 months. Normal bladder function was not achieved.
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Groot, G., Pagter, G. Effects of cisapride on constipation due to a neurological lesion. Spinal Cord 26, 159–161 (1988). https://doi.org/10.1038/sc.1988.25
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DOI: https://doi.org/10.1038/sc.1988.25
