Abstract
Background:
Total gastrointestinal transit times (GITT) and segmental colonic transit times (CTT) are commonly used to describe bowel function in individuals with spinal cord injury (SCI).
Study design:
Reproducibility study.
Objectives:
To describe inter- and intrasubjective as well as interobserver variations in GITT and segmental CTT in patients with SCI. Furthermore, to study associations between GITT or segmental CTT and colorectal symptoms.
Setting:
Spinal Cord Unit, Viborg Hospital, Denmark.
Methods:
Thirty SCI patients took 10 radio-opaque markers on 6 consecutive days and an abdominal X-ray was taken on day 7. The same procedure was repeated after 3 months. GITT and CTT were computed from the number of markers in the entire colorectum and in the left and the right colon. Intra- and interobserver variations were described as dispersion (numerical difference/mean).
Results:
Intersubjective variation was large for GITT (range: 0.6–6.3 days), right CTT (range: 0.1–5.5 days) and left CTT (range: 0–4.9 days). Intrasubjective variation was acceptable for GITT (dispersion: 0.28) but less good for right (dispersion: 0.63) and left CTT (dispersion: 0.68). Interobserver variation was very small. No correlations were found between GITT, right or left CTT and colorectal symptoms.
Conclusion:
GITT and right and left CTT are of limited value for clinical decision-making in individual patients but may be useful for comparison of groups of patients with SCI.
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Acknowledgements
This study was supported by grants from the Danish Association of Polio, Traffic and Accident Victims, The Ferdinand Salling Memorial Foundation and the Danish Research Council. The help from Susanne Døssing RN is much appreciated.
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Media, S., Christensen, P., Lauge, I. et al. Reproducibility and validity of radiographically determined gastrointestinal and segmental colonic transit times in spinal cord-injured patients. Spinal Cord 47, 72–75 (2009). https://doi.org/10.1038/sc.2008.88
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DOI: https://doi.org/10.1038/sc.2008.88
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