Abstract
Study design:
Randomized study.
Objectives:
To find out the incidence of deep vein thrombosis (DVT) in acute spinal cord injury (SCI) patients with and without therapeutic prophylaxis.
Setting:
Patients admitted in the department of Physical Medicine & Rehabilitation, SMS Medical College, Jaipur, India.
Methods:
All 297 patients received physical therapy measures and were randomly divided into two groups. 166 patients received prophylactic heparin, whereas 131 patients did not.
Results:
A total of three cases (1.8%) in study group and four cases (3%) in control group developed DVT. This difference was statistically insignificant (P>0.05).
Conclusion:
Incidence of DVT in SCI is low in our study.
Similar content being viewed by others
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Aito S, Pieri A, Andrea MD, Marcelli F, Cominelli E . Primary prevention of DVT and PE in acute SCI patients. Spinal Cord 2002; 40: 300–303.
Miranda AR, Haussoni HI . Mechanism of thrombosis in SCI. Haematol Oncol Clin North Am 2000; 14: 401–416.
Merli GJ, Crabbe S, Paluzzi RG, Fritz D . Etiology, incidence and prevention of DVT in acute SCI. Arch PMR 1993; 74: 1199–1205.
Saraf SK, Rana RJB, Sharma OP . Venous thromboembolism in acute spinal cord injury patients. Indian J Orthop 2007; 41: 194–197.
Watson N . Anticoagulant therapy in the prevention of venous thrombosis & PE in the SCI. Paraplegia 1978; 16: 265–269.
Perkash A, Perkash V, Perkash I . Experience with management of thromboembolism in patients with SCI: part I incidence, diagnosis & role of some risk factors. Paraplegia 1978; 16: 322–331.
Watson N . Anticoagulant therapy in the treatment of venous thrombosis & PE in acute SCI. Paraplegia 1974; 12: 197–201.
Silver JR . The prophylactic use of anticoagulant therapy in the patients of PE in 100 conservative spinal injury patients. Paraplegia 1974; 12: 188–196.
Hove EV . Prevention of thrombophlebitis in spinal injury patients. Paraplegia 1978; 16: 332–335.
Merli GJ, Herbison GJ, Ditunno JF, Weitz HH, Henzes JH, Park CH et al. Deep vein thrombosis : prophylaxis in acute spinal cord injury patients. Arch PMR 1988; 69: 661–664.
Rossi EC, Green D, Rosen JS, Spies SM, Yao JST . Sequential changes in factor VIII & platelet, preceding DVT in patients with SCI. Br J Haematol 1980; 45: 143–151.
Todd JW, Frisbie JH, Rossier AB, Adams DF, Als AV, Armenia RJ et al. DVT in acute SCI: a comparison of I125 fibrinogen leg scanning, IPG & venography. Paraplegia 1976; 14: 50–57.
Casas ER, Sanchez MP, Arias CR, Masip JP . Prophylaxis of venous thrombosis & PE in patients with acute traumatic spinal cord lesions. Paraplegia 1977; 15: 209–214.
Green D, Lee MY, Ito VY, Cohn T, Press J, Filbrandt PR et al. Prevention of thromboembolism after SCI using LMWH. Ann Int Med 1990; 113: 571–574.
Green D, Lee MY, Lim AC, Chmiel JS, Vetter M, Pang T et al. Fixed vs adjusted dose heparin in the prophylaxis and thromboembolism in SCI. JAMA 1988; 260: 1255–1258.
Doyle DJ, Turpie AG, Hirsh J, Best C, Kinch D, Levine MN et al. Adjusted SC heparin or IV heparin in patients with acute DVT. Ann Int Med 1987; 107: 441–445.
Swarczinski C . The value of serial calf girth measurements for monitoring DVT in SCI. J Neurosci Nurs 1991; 23: 306–314.
Watson N . Venous thrombosis & PE in SCI. Paraplegia 1968; 6: 113–121.
Walsh JJ, Tribe C . Phlebothrombosis & PE in paraplegia. Paraplegia 1965; 30: 209–213.
Beraldo PSS, Neves EGC, Alves CMF, Khan P, Cirilo ACM, Alencar MRB . Pyrexia in hospitalized SCI patients. Paraplegia 1993; 31: 186–191.
Chahal A . Proceedings of the annual scientific meeting the International Medical Society of Paraplegia discussing. Int J Paraplegia 1974; 12: 202 quoted from Casas ER, Sanchez MP, Arias CR, Masip JP. Prophylaxis of venous thrombosis & PE in patients with acute traumatic spinal cord lesions. Paraplegia, 1977–78; 15: 209–214.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Agarwal, N., Mathur, N. Deep vein thrombosis in acute spinal cord injury. Spinal Cord 47, 769–772 (2009). https://doi.org/10.1038/sc.2009.37
Received:
Revised:
Accepted:
Published:
Issue date:
DOI: https://doi.org/10.1038/sc.2009.37
Keywords
This article is cited by
-
Comparison of two pharmacological prophylaxis strategies for venous thromboembolism in spinal cord injury patients: a retrospective study
Spinal Cord (2019)
-
Effect of and satisfaction with www.elearnSCI.org for training of nurse students: a submodule pilot study
Spinal Cord (2014)
-
Pharmacological prophylaxis for deep vein thrombosis in acute spinal cord injury: an Indian perspective
Spinal Cord (2014)
-
Heparin for venous thromboembolism prophylaxis in patients with acute spinal cord injury: a systematic review and meta-analysis
Spinal Cord (2013)
-
Physical therapy versus heparin for prevention of deep venous thrombosis
Spinal Cord (2011)
