Abstract
Study design:
A clinical blind study was conducted to determine the efficacy of transdermal nitroglycerine treatment on the awareness of shoulder pain.
Objective:
This study aims to determine the effects of transdermal nitroglycerine on shoulder pain and on functional shoulder movement in patients with spinal cord injuries and shoulder tendinopathies. A second aim is to establish the side effects of the treatment.
Setting:
Hospital “La Fe” in Valencia, Spain.
Methods:
A total of 45 spinal cord injury patients, all of whom are wheelchair users with shoulder tendinopathy, were randomly divided into two groups: placebo (n=12) and experimental (n=33). The experimental group (EG) received transdermal treatment for 6 months in the form of a 1.25 mg nitroglycerine (NT) patch on the greater tubercle. A placebo patch was used with the placebo subjects. Functional shoulder movements were assessed by articular range of motion and pain, using a visual analogical scale.
Results:
NT treatment reduced the awareness of shoulder pain and increased the functional movement and range of articular motion in the shoulders of the EG members (P<0.05).
Conclusions:
We conclude that transdermal NT is an efficient method for treating shoulder tendinopathies in wheelchair users with spinal cord injuries.
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X GM is a Vali+D researcher in formation and thanks the Generalitat Valenciana.
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Giner-Pascual, M., Alcanyis-Alberola, M., Querol, F. et al. Transdermal nitroglycerine treatment of shoulder tendinopathies in patients with spinal cord injuries. Spinal Cord 49, 1014–1019 (2011). https://doi.org/10.1038/sc.2011.41
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DOI: https://doi.org/10.1038/sc.2011.41
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