Table 1 In-life observations

From: Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice

Parameter

Method

Frequency

Number of Mice

Remarks

Body weight

Gravimetry

Twice weekly

All

Individually

In-life observations

Non-systematic observation

Daily

All

Group observations

Daily

All*

After exposure

Individual observations according to checklist

Daily

One cage per exposure group

Immediately after removal from exposure chambers

Mortality

Observation

Daily

All mice

  1. * With the exception of those mice selected for carboxyhemoglobin measurement or urine collection on the day of determination.