Table 2 Clinical trial data downloaded from the Project Data Sphere portal.

From: A patient-level data meta-analysis of standard-of-care treatments from eight prostate cancer clinical trials

Trial

Study sponsor

No. of subjects *

Drug under investigation

Comparator arm treatment

ClinicalTrial.gov ID

1

AstraZeneca

1627

Bicalutamide

Placebo†

NCT00657904

2

AstraZeneca

635

Zibotentan

Placebo†

NCT00626548

3

AstraZeneca

287

Bicalutamide

Placebo†

NCT00672282

4

AstraZeneca

657

Bicalutamide

Placebo†

NCT00673205

5

Centocor

47

Siltuximab (with mitoxantrone plus prednisone)

Mitoxantrone plus prednisone

NCT00385827

6

Celgene

226

Lenalidomide (with docetaxel plus prednisone)

Docetaxel plus prednisone

NCT00988208

7

Pfizer

278

Sunitinib (with prednisone)

Prednisone

NCT00676650

8

Sanofi

370

Cabazitaxel (with mitoxantrone plus prednisone)

Mitoxantrone plus prednisone

NCT00417079

  1. All data files were downloaded on February 23rd, 2015.
  2. * Number of subjects for which survival data was available.
  3. † In addition to background treatments including LHRH agonist, antiandrogen or orchiectomy.
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