Table 1 Drugs used in screen.

From: Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells

Drug

Target

Libraries screened

Camptothecin

Topoisomerase I

1, 6, 7, 8, 9, 10

BIIB021

HSP90

1, 2, 3, 6, 7, 8, 9, 10, 2sims

AT13387

HSP90

1, 6, 7, 8, 9, 10

Bleomycin

Double strand breaks

1, 6, 7, 8, 10

Methotrexate

DHFR

1, 2, 3, 7, 8, 9, 10, 2sims

JQ1

BRD4

1, 2, 3, 4, 6, 7, 8, 9, 2sims

KW2478

HSP90

1, 6, 7, 9, 10

BMN 673

PARP1/2

1, 2, 3, 4, 6, 7, 8, 10, 2sims

MK1775

WEE1

1

17-AAG

HSP90

1, 7, 8, 9, 10

Etoposide

Topoisomerase II

1, 6, 7, 10

Decitabine

DNA methyltransferase

1, 6, 7, 8, 9, 10

PF04691502

HSP90

1, 8, 9, 10

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