Table 7 MRI sequences.

Gradient echo fieldmap for rs-fMRI distortion correction

voxel size=2.3 mm isotropic, FOV=202 mm, imaging matrix=88×88, 64 slices with 2.3 mm thickness, TR= 680 ms, TE1=5.19 ms, TE2=7.65 ms, flip angle=60°, bandwidth=389 Hz/pixel, prescan normalization, no partial fourier, duration=2 min 3 s

acq-GEfmap_run-01_magnitude1, acq-GEfmap_run-01_magnitude2, acq-GEfmap_run-01_phasediff

Spin echo EPI with reversed phase encoding for rs-fMRI distortion correction

voxel size=2.3 mm isotropic, FOV=202 mm, imaging matrix=88×88, 64 slices with 2.3 mm thickness, TR=2200 ms, TE=50 ms, flip angle=90°, echo spacing=0.67ms, phase encoding=A ≫ P / P ≫ A, bandwidth=1776 Hz/pixel, partial fourier 6/8, no pre-scan normalization, duration=29 s each

acq-SEfmapBOLDpost_dir-AP_epi, acq-SEfmapBOLDpost_dir-PA_epi, acq-SEfmapBOLDpre_dir-AP_epi, acq-SEfmapBOLDpre_dir-PA_epi

Resting-state fMRI (T2*-weighted gradient-echo EPI BOLD)

Axial acquisition orientation, phase encoding=A ≫ P, voxel size=2.3 mm isotropic, FOV=202 mm, imaging matrix=88×88, 64 slices with 2.3 mm thickness, TR=1400 ms, TE=30 ms, flip angle=69°, echo spacing=0.67 ms, bandwidth=1776 Hz/pixel, partial fourier 7/8, no pre-scan normalization, multiband acceleration factor=4, 657 volumes, slice order=interleaved, duration=15 min 30 s

acq-AP-run-01_bold

task-rest_acq-AP_run-01_native, task-rest_acq-AP_run-01_MNI2mm

Magnetization Prepared 2 Rapid Acquisition Gradient Echoes (MP2RAGE)

Sagittal acquisition orientation, one 3D volume with 176 slices, TR=5000 ms, TE=2.92 ms, TI1=700 ms, TI2=2500 ms, FA1=4°, FA2=5°, pre-scan normalization, echo spacing=6.9 ms, bandwidth=240 Hz/pixel, FOV=256 mm, voxel size= 1 mm isotropic, GRAPPA acceleration factor 3, slice order=interleaved, duration=8 min 22 s

acq-mp2rage_T1w, acq-mp2rage_T1map, acq-mp2rage_defacemask, inv-1_mp2rage,inv-2_mp2rage

acq-mp2rage_brain

T2-weighted

Sagittal acquisition orientation, one 3D volume with 176 slices, TR=3200 ms, TE=409 ms, FA=variable, pre-scan normalization, echo spacing=3.42 ms, bandwidth=751 Hz/pixel, FOV=256 mm, voxel size=1 mm isotropic, GRAPPA acceleration factor 2, duration=4 min 43 s

T2w

Fluid-attenuated inversion recovery (FLAIR) 2D (scanned in first 112 participants)

Axial acquisition orientation, 28 slices, TR=10000 ms, TE=90 ms, TI=2500 ms, FA=180°, pre-scan normalization, echo spacing=9.98 ms, bandwidth=199 Hz/pixel, FOV=220 mm, voxel size=0.9×0.9×4.0 mm³, slice order=interleaved, duration=4 min 42 s

acq-lowres_FLAIR

3D SPACE sequence with fluid-attenuated inversion-recovery preparation (introduced after first 112 participants)

Sagittal acquisition orientation, one 3D volume with 192 slices, TR=5000 ms, TE=395 ms, TI=1800 ms, FA=variable, pre-scan normalization, echo spacing=3.36 ms, bandwidth=781 Hz/pixel, FOV=250 mm, voxel size=1 mm isotropic, GRAPPA acceleration factor 2, duration=7 min 2 s

acq-highres_FLAIR

Diffusion-weighted Imaging (DWI, scanned in first 112 participants)

88 axial slices, voxel size=1.7 mm isotropic, 60 diffusion-encoding gradient directions, b-value of 1000 s/mm², 7 non-diffusion-weighted b0 distributed in the sequence, TR=7000 ms, TE=80 ms, FA=90°, bandwidth=1502 Hz/pixel, echo spacing=0.78 ms, FOV=220 mm, voxel dimension=1.7 mm isotropic, imaging matrix=128×128, acquired with 7/8 partial Fourier encoding and GRAPPA (acceleration factor 2, 32 ref. lines), 60 diffusion-encoding gradient directions, b-value=1000 s/mm², 7 b0 images, raw data filter, fat suppression (strong), advanced shim mode, no prescan normalization, interleaved acquisition, CMRR sequence, monopolar diffusion scheme, SENSE coil combine, multiband acceleration factor 2, phase encoding A ≫ P, duration=9 min 27 s

dwi

Spin echo images with reversed phase encoding for DWI distortion correction (scanned in first 112 participants)

Two volumes with A ≫ P and P ≫ A phase encoding, voxel size=1.7 mm isotropic, 88 axial slices, TR=7000 ms, TE=80 ms, FA=90°, bandwidth=1502 Hz/pixel, echo spacing 0.78 ms, FOV=220 mm, voxel dimension=1.7 mm isotropic, imaging matrix=128×128, acquired with 7/8 partial Fourier encoding and GRAPPA (acceleration factor 2, 32 ref. lines), fat suppression (strong), advanced shim mode, no prescan normalization, interleaved acquisition, CMRR sequence, SENSE coil combine, multiband acceleration factor 2, duration=1 min 59 s each

acq-SEfmapDWI_dir-AP_epi, acq-SEfmapDWI_dir-PA_epi

Diffusion-weighted Imaging (DWI, new version introduced after first 112 participants)

88 axial slices, voxel size=1.7 mm isotropic, 60 diffusion-encoding gradient directions, b-value of 1000 s/mm², 7 non-diffusion-weighted b0 distributed in the sequence, TR=7000 ms, TE=80 ms, FA=90°, bandwidth=1502 Hz/pixel, echo spacing=0.78 ms, FOV=220 mm, voxel dimension=1.7 mm isotropic, imaging matrix=128×128, acquired with 7/8 partial Fourier encoding and GRAPPA (acceleration factor 2, 32 ref. lines), 60 diffusion-encoding gradient directions, b-value=1000 s/mm², 7 b0 images, raw data filter, fat suppression, advanced shim mode, no prescan normalization, interleaved acquisition, CMRR sequence, monopolar diffusion scheme, SENSE coil combine, multiband acceleration factor 2, phase encoding A ≫ P, duration=8 min 38 s

dwi

Spin echo images with reversed phase encoding for DWI distortion correction (new version introduced after first 112 participants)

Two volumes with A ≫ P and P ≫ A phase encoding, voxel size=1.7 mm isotropic, 88 axial slices, TR=7000 ms, TE=80 ms, FA=90°, bandwidth=1502 Hz/pixel, echo spacing 0.78 ms, FOV=220 mm, voxel dimension=1.7 mm isotropic, imaging matrix=128×128, acquired with 7/8 partial Fourier encoding and GRAPPA (acceleration factor 2, 32 ref. lines), fat suppression, advanced shim mode, no prescan normalization, interleaved acquisition, CMRR sequence, SENSE coil combine, multiband acceleration factor 2, duration=1 min 10 s each

acq-SEfmapDWI_dir-AP_epi, acq-SEfmapDWI_dir-PA_epi

Gradient echo Susceptibility-weighted data for SWI and QSM estimation (introduced after first 112 participants)

Axial acquisition orientation, one 3D volume with 160 slices, TR=30 ms, TE=17.3 ms, FA=13°, bandwidth=150 Hz/pixel, FOV=205 mm, acquired with 6/8 phase partial Fourier and GRAPPA (acceleration factor 2, 24 ref. lines), no prescan normalization, interleaved acquisition, voxel size=0.8 mm isotropic, duration=7 min 50 s

acq-phase_GRE, acq-mag_GRE