Figure 3: Precision of image registration to atlas. | Scientific Data

Figure 3: Precision of image registration to atlas.

From: Brain-wide distribution of reporter expression in five transgenic tetracycline-transactivator mouse lines

Figure 3

(a) X-gal stained coronal section from a Prnp-tTA/tetO-lacZ mouse (case #388.12). (b) A corresponding custom virtual atlas map from the Allen Mouse CCF v.2. (c) Semi-transparent atlas map superimposed on the section image. (d,e) Higher magnifications from framed areas indicated in (c), with dashed lines indicating anatomical boundaries derived from the atlas. Note the spatial correspondence between atlas delineations and the underlying cytoarchitecture in the hippocampal region (see, e.g. CA1, CA3, DG, SUB) and midbrain (e.g. SNc, SNr), and the partial mismatch of the atlas delineations with the ventral part of the brain (arrowheads in c,e). CA1, cornu ammonis area 1; CA3, cornu ammonis area 3; cc, corpus callosum; Ctx, cerebral cortex; COA, cortical amygdalar area; DG, dentate gyrus ; GENd, medial geniculate complex; HF, hippocampal formation; MB, midbrain; MRN, midbrain reticular nucleus; PA, posterior amygdalar nucleus; PAG, periaqueductal gray; RN, red nucleus; PP, peripeduncular nucleus; RSP, retrosplenial area; SC, superior colliculus; SNc, substantia nigra compact part; SNr substantia nigra reticular part; SPF, subparafascicular nucleus; SUB, subiculum; VIS, visual cortex; VTA, ventral tegmental area. Scale bar, 1 mm.

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