Figure 2: Quality control, enrichment analysis, and reproducibility for PRO-seq and ChIP-exo data.
From: Epigenetic and transcriptional profiling of triple negative breast cancer
(a) Box-plot distribution of base quality scores are shown for H2A.Z ChIP-exo replicate 2. A score greater than 30 (green region) indicates a high confidence base call. (b) ChIP enrichment analysis plot that displays the cumulative percent of total reads found in a given percent of the mappable human genome. No ChIP enrichment would result in a diagonal trace. (c) Scatter plot correlation analysis for H2A.Z ChIP-exo biological replicates as measured by the Spearman correlation coefficient R-values (upper left corner).
