Figure 3

Overexpression and mutation of SEC61, SEC62 and SEC63 in human diseases. 40S, 40S ribosome subunit; 60S, 60S ribosome subunit; HCC, hepatocellular carcinoma; HNPCC, hereditary non-polyposis colorectal cancer; HNSCC, head and neck squamous cell carcinoma; NSCLC, non-small-cell lung cancer.