Figure 1
From: Ageing affects chondroitin sulfates and their synthetic enzymes in the intervertebral disc
Schematic of CS synthesis [adapted from Laboratories K. KEGG Pathway Maps: Glycosaminoglycans Synthesis, Japan, 2013]. The CS results from the polymerization of a succession of glycans on the serine residue of the Asn-X-Ser/Thr peptidic motif via different enzymatic reactions. The enzymes are represented in green, while the protein core is represented in orange.
