Table 4 Titers of neutralizing antibodies elicited by mutated JEV in mice

From: The molecular determinants governing the immunogenicity of Japanese encephalitis live attenuated vaccines

Viral strains

Seroconversion (%)

GMT

 

10 3 PFU

10 5 PFU

10 3 PFU

10 5 PFU

SA14-14-2

100

100

28.3

50.4

SA14-5-3

33.3

83.3

2.2

17.2

rJEV (E-177)

66.7

83

4.6

24.3

rJEV (E-264)

16.7

50

1.6

4

rJEV (177/264)

50

83

3.2

30.6

SA14-9-7

0

66.7

0

8.3

rJEV (E-279)

66.7

100

7.4

44.9

rJEV (E-315)

16.7

83.3

2.1

7.6

rJEV (E-279/315)

66.7

33.3

9.3

2.7

rJEV (E-177/264/279/315)

0

33.3

0

3

  1. Abbreviations: GMT, geometric mean titer; JEV, Japanese encephalitis virus; PFU, plaque-forming unit.
Back to article page