Figure 6
From: Fibromodulin reduces scar formation in adult cutaneous wounds by eliciting a fetal-like phenotype
FMOD enhanced TGFβ1-responsive Ctgf and α-Sma expression in adult RDFs. In the presence of TGFβ1, FMOD significantly increased expression of Ctgf (a) and a-Sma (b) of RDFs. Dosages: TGFβ1 (100 pM) and FMOD (200 nm). A two-sample t-test was used for statistical analysis. Data were normalized to untreated RDFs at time 0 (dashed lines) and shown as mean±the standard deviation. N=3. *P<0.05; a blue star indicates the significance in comparison with FMOD administration, and a magenta star indicates the significance in comparison with TGFβ1 administration.
