Key Points
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Explains the PICO statement and the basics of randomisation.
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Readers will understand the basics of statistical testing, sample size calculations and the basics of bias.
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Readers will also understand the role of Clinical Trials Units and why they are important when considering an experimental design
Abstract
This practical paper explains how to design an randomised controlled trial (RCT) for those who have little prior knowledge of the topic. It covers the basics of radomisation, statistical testing, sample size caluclations, bias and the role of Clinical Trial Units.
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Brocklehurst, P., Hoare, Z. How to design a randomised controlled trial. Br Dent J 222, 721–726 (2017). https://doi.org/10.1038/sj.bdj.2017.411
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DOI: https://doi.org/10.1038/sj.bdj.2017.411
