Figure 2
Phenotypic analysis of adipose tissue in chemerin-deficient mice.
(a) Weights of epididymal fat in 10-week-old chemerin (+/+) and (−/−) mice. (b) H&E sections of epididymal fat tissue from chemerin (+/+) and (−/−) mice. (100×) (c) Expression of adipocyte markers in epididymal adipose tissue. (n = 4–5/genotype). (d) Immunohistochemical detection of Mac3 in epididymal adipose tissue of 10-week-old (+/+) and (−/−) mice. Macrophages are stained brown. (400×) (e) Macrophage infiltration into epididymal fat tissue was quantified as the ratio of Mac3-positive cells to total cells. Data are mean ± SEM. (n = 3/genotype). (f) Serum leptin and adiponectin concentrations in chemerin (+/+) and (−/−) mice. (n = 6/genotype).
