Table 3 List of 12 
functions that evaluate 
binding strength of the core region (P6–P2′) and 
solvent accessibility of two flanking regions (P7–P14 and P3′–P6′)
functions that evaluate 
binding strength of the core region (P6–P2′) and 
solvent accessibility of two flanking regions (P7–P14 and P3′–P6′)
| Physical property | Position on the furin cleavage site motif | Description8 |
|---|---|---|---|
| ZIMJ68010425 | P2 P4 P5 P6 | Positive charge and isoelectric point |
| ZIMJ68010425 | P2 P3 | Positive charge and isoelectric point |
| Cysteine8 | P2–P6 | Disulfide bond formation potential and negative charge |
| P4 | Aliphatic residue or positively charged residue | |
| FAUJ88011127 | P4–P6 | Positive charge compensation |
| BULH74010228 | P1′ | Volume |
| BULH74010228 | P1′ – P3′ | Volume |
| KARP85010329 | P1′ P2 P4 P5 P6 | Flexibility |
| KARP85010329 | P1′ – P3′ | Flexibility |
| EISD84010114 | P7–P10 | Hydrophobicity |
| EISD84010114 | P3′–P6′ | Hydrophobicity |
| EISD84010114 | P11–P14 | Hydrophobicity |
functions
